Anastrozole 1mg 28 Tab (ARIMIDEX)

Anastrozole 1mg 28 Tab (ARIMIDEX)

Brand: Pisa Labs
Product Code: anastrozole_1mg-28t
Reward Points: 600
Availability:
In Stock
Price: $75.00$125.00
Description

Anastrozole 1MG 28 TAB (ARIMIDEX)

 

Brand: Arimidex
Generic: Anastrozole
 

Patient Education - English

  • Generic Name: anastrozole
  • Pronounced: an AS troe zole
  • Brand Name: Arimidex

--------------------------------------------------------------------------------------------

What is the most important information I should know about anastrozole?

  • Anastrozole is the generic form of Arimidex 

  • Anastrozole is indicated in treating breast cancer in postmenopausal women It is often given to women whose cancer has progresed ever after taking Tamoxifen (aka Nolvadex or Soltamox)

  • Anastrozole is also used in an anabolic steroid cycles that contain aromatizing steroids, the user protects against gynecomastia and water retention. This will also assist in protecting against high blood pressure.

 

 

Do not use anastrozole if you are pregnant. It could harm the unborn baby.

Anastrozole may not work as well if you take it together with estrogen medication (such as hormone replacement therapy, estrogen creams, or birth control pills, injections, implants, skin patches, and vaginal rings).

Anastrozole may increase your risk of a stroke or blood clot. Call your doctor at once if you have sudden numbness or weakness, (especially on one side of the body), sudden severe headache, slurred speech, or problems with vision or balance.

 

What is anastrozole?

Anastrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Anastrozole is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).

Anastrozole may also be used for purposes not listed in this medication guide.

 

What should I discuss with my healthcare provider before taking anastrozole?

You should not use this medication if you are allergic to anastrozole, if you are breast-feeding a baby, or if you have not yet completed menopause. Anastrozole is not for use in men or children.

To make sure anastrozole is safe for you, tell your doctor if you have:

  • heart disease;
  • circulation problems;
  • a history of stroke or blood clot;
  • severe liver disease;
  • high cholesterol; or
  • osteoporosis or low bone mineral density.

Anastrozole can decrease bone mineral density, which may increase your risk of developing osteoporosis. Your bone mineral density may need to be tested before and during treatment with anastrozole.

FDA pregnancy category D. Do not use anastrozole if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether anastrozole passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using anastrozole.

You may need to take a pregnancy test before using anastrozole, to make sure you are not pregnant.

 

How should I take anastrozole?

Anastrozole is usually taken once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take anastrozole with or without food.

You may need to keep taking this medication for up to 5 years. Follow your doctor's instructions.

Store at room temperature away from moisture and heat.

 

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

 

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

 

What should I avoid while taking anastrozole?

This medicine can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Patients and caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of anastrozole?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • sudden numbness or weakness, especially on one side of the body;
  • sudden severe headache, confusion, problems with vision, speech, or balance;
  • a bone fracture;
  • swollen glands;
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • swelling in your hands or feet; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • weakness, hot flashes;
  • joint pain or stiffness, problems with your fingers while gripping;
  • sore throat, headache, back pain, bone pain;
  • depression, mood changes, sleep problems (insomnia);
  • mild nausea, vomiting; or
  • mild rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect anastrozole?

Anastrozole may not work as well if you take it together with an estrogen medication (such as hormone replacement therapy, estrogen creams, or birth control pills, injections, implants, skin patches, and vaginal rings). Before you start taking anastrozole, tell your doctor if you also take tamoxifen or estrogen.

Other drugs may interact with anastrozole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about anastrozole.


 

Adult Dosing .

Dosage forms:  1

Special Note[uses, dosing may vary]  Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

breast CA, advanced or metastatic postmenopausal

[1 mg PO qd]

early postmenopausal breast CA, adjuvant tx

[1 mg PO qd]

*Ovulation Induction: [1-5 mg PO qd x5 days]  Start: day 3 of menstrual cycle

Renal Dosing: [no adjustment]

Hepatic Dosing: mild-mod impairment/cirrhosis: no adjustment; severe impairment: not defined

Peds Dosing

Peds dosing is currently unavailable or not applicable for this drug.

Contraindications/Cautions .

  • hypersens. to drug/class/compon.
  • pregnancy
  • premenopausal pts
  • caution if ischemic heart dz

Drug Interactions

Overview: 

anastrozole, aromatase inhibitor

Interaction Characteristics: None

Avoid/Use Alternative

  • DHEA
  • estradiol (contraceptive)
  • estradiol (hormone replacement)
  • estrogens, conjugated (hormone replacement)
  • estrogens, esterified (hormone replacement)
  • estropipate (hormone replacement)
  • ethinyl estradiol (contraceptive)
  • ethinyl estradiol (hormone replacement)
  • mestranol (contraceptive)
  • tamoxifen

Adverse Reactions

Serious Reactions

  • fractures
  • osteoporosis
  • endometrial CA
  • thromboembolism
  • MI
  • stroke
  • angina
  • HTN
  • cataracts
  • anemia
  • leukopenia
  • erythema multiforme
  • Stevens-Johnson syndrome

Common Reactions

  • hot flashes
  • asthenia
  • pain
  • arthralgia
  • arthritis
  • nausea/vomiting
  • headache
  • pharyngitis
  • depression
  • rash
  • HTN
  • lymphedema
  • insomnia
  • edema
  • weight gain
  • dyspnea
  • abdominal pain
  • constipation
  • hypercholesterolemia
  • osteoporosis
  • fractures
  • cough
  • bone pain
  • diarrhea
  • breast pain
  • paresthesia
  • infection
  • cataracts
  • myalgia
  • thromboembolism
  • angina

Safety/Monitoring .

Pregnancy: X

Lactation: Safety Unknown

Monitoring Parameters: pregnancy test at baseline; consider BMD, lipid panel

Look/Sound-Alike Drug Names: anastrozole confused with: anagrelide; letrozole

Pharmacology .

Metabolism: liver primarily; CYP450: none

Excretion: urine 60% (10% unchanged), feces; Half-life: 50h

Subclass: Hormonal Oncologics 4: Antiestrogens; Infertility

Mechanism of Action
inhibits enzymatic androgen conversion to estrogen, reducing hormone receptor positive cancer cell growth (aromatase inhibitor)

Manufacturer/Pricing .

Manufacturer: KNOLL PHARMA & PISA LABS, Generic Formula/Presentation

Approximate Retail Price1 mg (30 ea): $128.00


Warranty Information

This is a Generic Drug and not a brand name or patented medicine; Because of its generic form, a compulsory licence(s) were issued in numerous countries allowing their fabrication, importation, exportation and distribution where legally permitted; and are not in violation of any accords in regards to trademarks or patents. Confirm you are able to order and receive these generic pharmaceuticals into your country prior to ordering, as some countries may not allow their importation.  
Reviews (0)

Write a review



Note: HTML is not translated!

Bad            Good

Related Products