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FDA Drug Import News

Import Rules Regarding Personal Medicine Orders:

Current FDA policy is not a law or a regulation, but serves as guidance for FDA personnel.

The importation of certain unapproved prescription medications for personal use may be allowed in some circumstances where these factors apply:


    1). The Drug is for personal use and is a 3-month supply or less and not for resale or commercialization.

    2). If no drug commercialization or drug promotion to U.S. residents by pharmacy companies involved in the distribution of the necessary drug exists.

    3). If an individual seeking to import the drug affirms in writing, that it is for the patient's private use and provides the name and address of the licensed American physician responsible for treatment.

    4). Provides evidence that the drug is for continuation of a treatment begun in a foreign country.

    5). The intended use is for a serious condition for which effective treatment may not be available domestically.

    6). If the product is not considered to represent an unreasonable health issue.

    7). Overnite FedEx shipments require copy of your identification and the prescription.

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Rx News

Propranolol hcl. {generic INDERAL LA} 10mg x28s Tablets

Propranolol hcl. {generic INDERAL LA} 10mg x28s Tablets
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Price: $22.00
Product ID : propranolol_10x28s
Manufacturer: MHRA UK Approved Generic
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Description

Patient Education - English

  • Generic Name: propranolol
  • Pronounced: pro PRAN oh lol
  • Brand Names: Inderal, Inderal LA, InnoPran XL

What is the most important information I should know about propranolol?

You should not use this medication if you are allergic to propranolol, or if you have asthma or certain heart conditions, especially second or third degree heart block.

Do not stop taking propranolol without first talking to your doctor. Stopping suddenly may make your condition worse.

If you need to have any type of surgery, you may need to temporarily stop using propranolol. Be sure the surgeon knows ahead of time that you are using propranolol.

Avoid drinking alcohol. It may increase your blood levels of propranolol.

Propranolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

What is propranolol?

Propranolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches.

Propranolol may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking propranolol?

You should not use this medication if you are allergic to propranolol, or if you have asthma or certain heart conditions, especially second or third degree heart block.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking propranolol, tell your doctor if you have:

  • bronchitis, emphysema, or other breathing disorders;
  • diabetes;
  • low blood pressure;
  • a heart problem such as heart block, sick sinus syndrome, slow heart rate, or congestive heart failure;
  • depression;
  • liver or kidney disease;
  • a thyroid disorder;
  • pheochromocytoma; or
  • problems with circulation (such as Raynaud's syndrome).

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Propranolol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take propranolol?

Take propranolol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medication with a full glass of water.

Take propranolol at the same time every day.

Do not crush, chew, break, or open an extended-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not skip doses or stop taking propranolol without first talking to your doctor. Stopping suddenly may make your condition worse.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon that you are using propranolol. You may need to briefly stop using propranolol before having surgery.

Propranolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

Store propranolol at room temperature away from moisture and heat.

What happens if I miss a dose?

For regular (short-acting) propranolol: Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the missed dose and take the medicine at the next regularly scheduled time.

For extended-release propranolol (Inderal LA, InnoPran XL and others): Take the missed dose as soon as you remember. If your next dose is less than 8 hours away, skip the missed dose and take the medicine at the next regularly scheduled time.

Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include slow or uneven heartbeats, dizziness, weakness, or fainting.

What should I avoid while taking propranolol?

Avoid drinking alcohol. It may increase your blood levels of propranolol.

What are the possible side effects of propranolol?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • fast, slow, or uneven heartbeats;
  • feeling light-headed, fainting;
  • feeling short of breath, even with mild exertion;
  • swelling of your ankles or feet;
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • depression, confusion, hallucinations; or
  • cold feeling in your hands and feet.

Less serious side effects may include:

  • nausea, vomiting, diarrhea, constipation, stomach cramps;
  • decreased sex drive, impotence, or difficulty having an orgasm;
  • sleep problems (insomnia); or
  • tired feeling.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect propranolol?

Tell your doctor about all other medications you use, especially:

  • clonidine (Catapres);
  • digitalis (digoxin, Lanoxin);
  • dobutamine (Dobutrex);
  • haloperidol (Haldol);
  • isoproterenol (Isuprel);
  • a blood thinner such as warfarin (Coumadin);
  • an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Janimine, Tofranil), and others;
  • an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);
  • aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), and others;
  • doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin);
  • a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), diltiazem (Cartia, Cardizem), or verapamil (Calan, Verelan, Isoptin);
  • amiodarone (Cordarone, Pacerone), propafenone (Rythmol), quinidine (Quinaglute, Quinidex, Quin-Release); or
  • an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

This list is not complete and there may be other drugs that can interact with propranolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about propranolol.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Pill Pictures

Inderal (propranolol) 60 mg

Inderal (propranolol) 60 mg

Why is Propranolol hydrochloride prescribed?

Inderal, a type of medication known as a beta blocker, is used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), changes in heart rhythm, prevention of migraine headache, hereditary tremors, hypertrophic subaortic stenosis (a condition related to exertional angina), and tumors of the adrenal gland. It is also used to reduce the risk of death from recurring heart attack. InnoPran XL is used to treat high blood pressure.

When Inderal and InnoPran XL are used for the treatment of high blood pressure, they are effective alone or combined with other high blood pressure medications, particularly thiazide-type diuretics. Beta blockers decrease the force and rate of heart contractions, reducing the heart's demand for oxygen and lowering blood pressure.

Most important fact about Propranolol hydrochloride

If you have high blood pressure, you must take Inderal regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Inderal; and you must continue taking it even if you are feeling well. Inderal does not cure high blood pressure; it merely keeps it under control.

How should you take Propranolol hydrochloride?

Inderal works best when taken before meals. Take it exactly as prescribed, even if your symptoms have disappeared. InnoPran XL should be taken once before bedtime, with or without food.

Try not to miss any doses. If Propranolol hydrochloride is not taken regularly, your condition may worsen.

  • If you miss a dose...
    Take it as soon as you remember. If it is within 8 hours of your next scheduled dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.
  • Storage instructions...
    Store at room temperature in a tightly closed, light-resistant container. Protect from freezing or excessive heat.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Propranolol hydrochloride.

  • Side effects of Inderal may include:
    Allergic reactions, congestive heart failure, decreased white blood cells, depression, light-headedness, low blood pressure, nausea, slow heartbeat,
  • Side effects of InnoPran XL may include:
    Constipation, dizziness, fatigue

Why should Propranolol hydrochloride not be prescribed?

If you have inadequate blood supply to the circulatory system (cardiogenic shock), certain types of irregular heartbeat, a slow heartbeat, bronchial asthma, or severe congestive heart failure, you should not take Propranolol hydrochloride

Special warnings about Propranolol hydrochloride

If you have a history of congestive heart failure, your doctor will prescribe Inderal cautiously.

Inderal should not be stopped suddenly. This can cause increased chest pain and heart attack. Dosage should be gradually reduced.

If you suffer from asthma or other bronchial conditions, coronary artery disease, or kidney or liver disease, Propranolol hydrochloride should be used with caution.

Ask your doctor if you should check your pulse while taking Inderal. This medication can cause your heartbeat to become too slow.

This medication may mask the symptoms of low blood sugar or alter blood sugar levels. In addition, diabetics who experience a severe drop in blood sugar after taking insulin may suffer a spike in blood pressure if they are also taking Inderal.

Notify your doctor or dentist that you are taking Inderal if you have a medical emergency, and before you have surgery or dental treatment.

Possible food and drug interactions when taking Propranolol hydrochloride

If Inderal is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Inderal with the following:


Alcohol
Aluminum hydroxide gel
Antipyrine
Calcium-blocking blood pressure drugs such as diltiazem, nifedipine, and verapamil
Certain high blood pressure medications such as reserpine
Chlorpromazine
Cimetidine
Epinephrine
Haloperidol
Insulin
Lidocaine
Nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen
Oral diabetes drugs such as glyburide
Phenobarbitone
Phenytoin
Rifampin
Theophylline
Thyroid medications such as levothyroxine

Special information if you are pregnant or breastfeeding

The effects of Inderal during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Inderal appears in breast milk and could affect a nursing infant. If Propranolol hydrochloride is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Propranolol hydrochloride is finished.

Recommended dosage for Propranolol hydrochloride

ADULTS

All dosages of Inderal, for any problem, must be tailored to the individual. Your doctor will determine when and how often you should take Propranolol hydrochloride. If you are over 65, the doctor will probably start with a relatively low dosage. Remember to take it exactly as directed.

Hypertension

The usual starting dose of Inderal is 40 milligrams 2 times a day. This dose may be in combination with a diuretic. Dosages are gradually increased to between 120 milligrams and 240 milligrams per day for maintenance. In some cases, a dose of 640 milligrams per day may be needed. Depending on the individual, maximum effect of Propranolol hydrochloride may not be reached for a few days or even several weeks. Some people may do better taking Propranolol hydrochloride 3 times a day.

The usual starting dose of InnoPran XL is 80 milligrams once daily at bedtime. Depending on your response, the doctor may increase your dose to 120 milligrams.

Angina Pectoris

The usual daily dosage is 80 milligrams to 320 milligrams, divided into 2, 3, or 4 smaller doses. When your treatment is being discontinued, your doctor will reduce the dosage gradually over a period of several weeks.

Irregular Heartbeat

The usual dose is 10 milligrams to 30 milligrams 3 or 4 times a day, before meals and at bedtime.

Heart Attack

The usual daily dosage is 180 milligrams to 240 milligrams divided into smaller doses. The usual maximum dose is 240 milligrams, although your doctor may increase the dose when treating heart attack with angina or high blood pressure.

Migraine

The usual starting dosage is 80 milligrams per day divided into smaller doses. Dosages can be increased gradually to between 160 milligrams and 240 milligrams per day. If this dose does not relieve your symptoms in 4 to 6 weeks, your doctor will slowly take you off the drug.

Tremors

The usual starting dose is 40 milligrams, 2 times per day. Symptoms will usually be relieved with a dose of 120 milligrams per day; however, on occasion, dosages of 240 milligrams to 320 milligrams per day may be necessary.

Hypertrophic Subaortic Stenosis

The usual dose is 20 milligrams to 40 milligrams, 3 to 4 times a day, before meals and at bedtime.

Before Adrenal Gland Surgery

The usual dose is 60 milligrams a day divided into smaller doses for 3 days before surgery in combination with an alpha-blocker drug.

Inderal may also be taken by people with inoperable tumors in doses of 30 milligrams a day, divided into smaller doses.

CHILDREN

Inderal will be carefully individualized for use in children and is used only for high blood pressure. Doses in children are calculated by body weight, and range from 2 milligrams to 4 milligrams per 2.2 pounds daily, divided into 2 equal doses. The maximum dose is 16 milligrams per 2.2 pounds per day.

If treatment is stopped, Propranolol hydrochloride must be gradually reduced over a 7- to 14-day period.

Inderal is also available in a sustained-release formulation, called Inderal LA, for once-a-day dosing.

Pill Pictures

Inderal (propranolol) 60 mg
Inderal (propranolol) 60 mg
Inderal LA (propranolol) 120 mg
Inderal LA (propranolol) 120 mg
Inderal LA (propranolol) 60 mg
Inderal LA (propranolol) 60 mg
Inderal LA (propranolol) 80 mg
Inderal LA (propranolol) 80 mg
Inderal LA (propranolol) 160 mg
Inderal LA (propranolol) 160 mg
InnoPran XL (propranolol) 80 mg
InnoPran XL (propranolol) 80 mg
InnoPran XL (propranolol) 120 mg
InnoPran XL (propranolol) 120 mg
propranolol (generic) 80 mg
propranolol (generic) 80 mg
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propranolol (generic) 160 mg
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propranolol (generic) 20 mg
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propranolol (generic) 80 mg
propranolol (generic) 80 mg
propranolol (generic) 80 mg

Overdosage

  • No specific information on Inderal overdosage is available; however, overdose symptoms with other beta blockers include:
    Extremely slow heartbeat, irregular heartbeat, low blood pressure, severe congestive heart failure, seizures, wheezing

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately

All our generic medicines are produced in W.H.O-Geneva, MHRA or FDA Inspected and Approved Laboratories. This is a Generic drug and not a brand name medicine; because of it's generic form a compulsary licence(s) were issued in numerous countries allowing their fabrication, importation and distribution where they are legally permitted; and not in violation of any accords in regards to trademarks and patents. Be sure you are able to import these generic pharmaceuticals into your country prior to ordering; as some countries will not allow their importation.

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