AMOXICILLIN/BROMHEXINE (generic AMOXIBRON) 125mg /4mg x60s Tablets
| Indications |
Upper and lower resp tract infections. |
| Dosage |
Adult: PO Upper and lower resp tract infections Per cap contains amoxicillin 250 mg and bromhexine 8 mg: 1-2 cap 8 hrly.
|
| Contraindications |
Penicillin allergy, lactation. |
| Special Precautions |
Pregnancy, renal and hepatic disease and history of peptic ulcer . Infectious mononucleosis. |
| Adverse Drug Reactions |
Headache, nausea, dizziness, vomiting, diarrhoea, black hairy tongue, maculopapular rash, urticaria, eosinophilia, hemolytic anemia, thrombocytopenia. Potentially Fatal: Anaphylaxis, pseudomembranous colitis, acute cytoloytic hepatitis and Stevens-Johnson syndrome. |
| Drug Interactions |
Live oral typhoid vaccine should not be given 3 days before or 3 days after amoxicillin admin as immune response may be attenuated. Amoxicillin increases the anticoagulant response of coumarins. Amoxicillin may reduce OC pill absorption leading to breakthrough bleeding or pregnancy. Amoxicillin reduces the renal clearance of methotrexate and pemetrexate. Amoxicillin level significantly reduced when given with or 2 hr after acacia admin. Bromhexine enhances the penetration of amoxicillin into bronchial secretions.
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| Food Interaction |
For caution against potential drug-food interactions ... |
| Lab Interference |
For caution against possible drug interference in lab test results ... |
| Mechanism of Action |
For details of the mechanism of action, pharmacology and pharmacokinetics and toxicology ... |
| CIMS Class |
Penicillins |
| ATC Classification |
J01CA04 - Amoxicillin ; Belongs to the class of penicillins with extended spectrum. Used in the systemic treatment of infections. R05CB02 - Bromhexine ; Belongs to the class of mucolytics. Used in the treatment of wet cough. |
This is a Generic drug and not a brand name medicine; because of it's generic form a compulsary licence(s) were issued in numerous countries allowing their fabrication, importation and distribution where they are legally permitted; and not in violation of any accords in regards to trademarks and patents. Be sure you are able to import these generic pharmaceuticals into your country prior to ordering; as some countries will not allow their importation.
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