Tindamax-Generic (tinidazole) 500mg x10 tabs, Tinifas

What is tinidazole?

Tinidazole is an antibiotic that fights bacteria in the body.

Tinidazole is used to treat certain infections caused by bacteria, such as infection of the intestines or vagina. It is also used to treat certain sexually transmitted infections.

Tinidazole may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about tinidazole?

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Tinidazole will not treat a viral infection such as the common cold or flu. Do not drink alcohol while taking tinidazole and for at least 3 days after finishing the medication. You may have unpleasant side effects such as fast heartbeats, severe nausea, vomiting, sweating, and warmth or tingling under your skin.

A medicine similar to tinidazole has caused cancer in laboratory animals. It is not known if tinidazole would have the same effect in animals, or in humans. Talk with your doctor about your specific cancer risk.

What should I discuss with my healthcare provider before taking tinidazole?

Do not use this medication if you are allergic to tinidazole, or:

• if you are in the first 3 months of pregnancy;

• if you are breast-feeding a baby (you should stop breast-feeding during treatment with tinidazole); or

• if you are allergic to metronidazole (Flagyl).

Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease (or if you are on dialysis);

• epilepsy or other seizure disorder;

• a blood cell disorder such as anemia; or

• a weak immune system.

If you have any of these conditions, you may not be able to use tinidazole, or you may need dosage adjustments or special tests during treatment.

How should I take tinidazole?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take tinidazole with a full glass (8 ounces) of water. Take this medication with food.

Some infections are treated with only one dose. Follow your doctor's instructions.

Do not give this medication to another person, even if they have the same symptoms you have.

If you are treating a sexually transmitted infection, make sure your sexual partner seeks medical attention to be treated also.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Tinidazole will not treat a viral infection such as the common cold or flu. Store tinidazole at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a tinidazole overdose are not known.

What should I avoid while taking tinidazole?

Do not drink alcohol while taking tinidazole and for 3 days after finishing the medication. You may have unpleasant side effects such as fast heartbeats, severe nausea, vomiting, sweating, and warmth or tingling under your skin.

Check the label of the products and other medicines you use, such as mouthwash or cough and cold medicines. Alcohol in these products can also cause a reaction if you use them while taking tinidazole.

Tinidazole side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• seizures;

• fever, chills, body aches, flu symptoms;

• numbness, burning, pain, or tingly feeling; or

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.

Less serious side effects may be more likely to occur, such as:

• vaginal yeast infection (itching, white discharge);

• an unpleasant metallic taste in your mouth;

• nausea, vomiting, loss of appetite, indigestion;

• constipation, diarrhea, stomach cramps;

• dark-colored urine;

• headache, dizziness;

• muscle or joint pain;

• dry mouth, thirst, change in the color of your tongue;

• white patches or sores inside your mouth or on your lips; or

• minor skin rash or itching.

Tinidazole Dosing Information

Usual Adult Dose for Trichomoniasis:

2 g orally once with food
The sexual partners should be treated with the same dose at the same time.

Usual Adult Dose for Giardiasis:

2 g orally once with food

Usual Adult Dose for Amebiasis:

Intestinal: 2 g orally once a day with food for 3 days
Amebic liver abscess: 2 g orally once a day with food for 3 to 5 days

Usual Adult Dose for Bacterial Vaginosis:

Nonpregnant, adult women: 2 g orally once a day with food for 2 days or 1 g orally once a day with food for 5 days

Usual Pediatric Dose for Trichomoniasis:

2 g orally once with food
The sexual partners should be treated with the same dose at the same time.

Usual Pediatric Dose for Giardiasis:

3 years or older: 50 mg/kg (up to 2 g) orally once with food

Usual Pediatric Dose for Amebiasis:

3 years or older:
Intestinal: 50 mg/kg (up to 2 g) orally once a day with food for 3 days
Amebic liver abscess: 50 mg/kg (up to 2 g) orally once a day with food for 3 to 5 days
Close monitoring is recommended when treatment durations exceed 3 days.

What other drugs will affect tinidazole?

If you are taking a blood thinner such as warfarin (Coumadin), you may need a dose adjustment or special tests while you are taking tinidazole, and for up to 8 days after you stop taking it.

Before taking tinidazole, tell your doctor if you are using any of the following drugs:

• amiodarone (Cordarone, Pacerone);

• cimetidine (Tagamet);

• cholestyramine (Questran, Prevalite);

• cyclosporine (Neoral, Sandimmune) or tacrolimus (Prograf);

• dexamethasone (Decadron, Hexadrol);

• fluorouracil (Adrucil, Efudex, Carac, Flurorplex);

• griseofulvin (Fulvicin, Grifulvin, Grisactin);

• lithium (Lithobid, Eskalith, and others);

• rifampin (Rifadin, Rimactane, Rifater);

• St. John's wort;

• antibiotics such as azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), itraconazole (Sporanox), or ketoconazole (Nizoral);

• HIV medication such as nevirapine (Viramune), delavirdine (Rescriptor), or efavirenz (Sustiva); or

• seizure medication such as carbamazepine (Carbatrol, Tegretol), phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).

If you are using any of these drugs, you may not be able to use tinidazole, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect tinidazole. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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